ea0035p458 | Diabetes complications | ECE2014
Szopa Magdalena
, Osmenda Grzegorz
, Wilk Grzegorz
, Matejko Bartlomiej
, Guzik Tomasz
, Malecki Maciej
Mutations in the (glucokinase) GCK gene are, along with the HNF1A gene mutations, the most frequent cause of (maturity onset diabetes of the young) MODY. Heterozygous loss-of-function GCK mutations result in a moderate fasting hyperglycemia. The GCK-MODY patients are usually free from microvascular complications; however, little is known about atherosclerosis and intermediate related phenotypes. We aimed to examine intima-media thickness (IMT) and endothelial function in GCK-M...